Historically, many prior trials in primary brain tumors like gliomas have failed to produce substantial improvements in patient outcomes. However, the use of tissue-agnostic drugs for primary brain tumors is just emerging, which we discussed in a state-of-the-art review in Trends in Cancer.

Local Xylocarpus granatum leaves were extracted by ethyl acetate solvent and characterized by TLC fingerprinting and 2D 1H NMR spectroscopy to contain phenolic compounds as well as several organic and amino acids as metabolic byproducts, such as succinic acid and acetic acid.

To define and classify megameatus anomalies, the parameters of a considerable number of cases were investigated and compared with those of normal children.